Twelfth seed Patty Schnyder of Switzerland fought back to upset sixth seed Elena Dementieva 6-7, 7-6, 6-2 to reach the quarter-finals.
Andy Roddick and Guillermo Coria raced into the fourth round with crushing victories.
The Wimbledon champion crushed China's Li Na 6-0, 6-2 to become the fifth Russian woman to reach the fourth round.
Rafael Nadal will become the first man to win 21 Grand Slam titles if he defeats the Russian in Melbourne.
Even after 20 Grand Slam titles, the tears gushing down Roger Federer's cheeks after winning his sixth Australian Open crown on Sunday showed the competitive fires still rage within the 36-year-old Swiss.
Images from Day 7 of the 2022 Australian Open at Melbourne Park on Sunday.
'With all the foot issues, just turned 36, he adds his 22nd Major'
The top seed began her Australian Open quest with a pulverising 6-0, 6-0 win over 15-year-old Olivia Lukaszewicz on Monday.
Sebastian Korda is just the third American to reach the quarter-finals at the Australian Open.
Images from Day 1 of the Australian Open in Melbourne on Monday.
The 28-year-old said beating American great Williams was the finest win of her career, outstripping her upset of world number one Ash Barty at last year's US Open.
Germany's Tommy Haas beat third seed Nikolay Davydenko 6-3, 2-6, 1-6, 6-1, 7-5 to enter the semi-final.
Serena Williams battled her way into the Australian Open semi-finals with a 3-6, 6-2, 8-6 win over Israeli Shahar Peer.
Marcos Baghdatis failed to repeat his heroics of last year and was beaten by Frenchman Gael Monfils in the second round of the Australian Open.
Serena Williams ended the fairytale run of Mirjana Lucic-Baroni at the Australian Open on Thursday with a crushing 6-2, 6-1 win that set up a final against her sister Venus.
Naomi Osaka will defend her title at the US Open, organisers said on Wednesday, after she withdrew from this year's French Open and Wimbledon on mental health grounds.
Images from Day 2 of the 2024 Australian Open in Melbourne on Monday.
Here is a breakdown of Roger Federer's Grand Slam numbers.
Jannik Sinner has sprinted past opponents at the Australian Open in his quest for a maiden Grand Slam but could end up running a marathon in the final against Daniil Medvedev on Sunday, when Melbourne Park will crown a new king.
It was the first Grand Slam triumph for Polasek, 35, who came out of retirement in 2018
Nadal was able to see the funny side and kept on laughing.
Florida-born Collins battled hard in the first set on a stifling day at Rod Laver Arena but ended up steamrolled 7-6(2), 6-0 by eighth seed Kvitova.
The Australian Open will lose one of its giant killers when South Korean Chung Hyeon meets American Tennys Sandgren in an unlikely quarter-final showdown at the Rod Laver Arena on Wednesday.
'It ranks right at the top. Under the circumstances, playing against Nadal, such an important match, it's amazing," the 31-year-old told reporters after needing barely two hours to extend his perfect record in seven Australian Open finals'
Alcaraz's hero Rafael Nadal, who won two Wimbledons and once beat Roger Federer in five sets once said Alcaraz's victory over Djokovic felt similar.
The Aussie ace said he rallied after that to take the tie-break 7-0 and tie the Davis Cup match against Ferrero at 2-all.
Naomi Osaka gave Jennifer Brady a lesson in Grand Slam tennis as she cruised to a 6-4, 6-3 win to claim her second Australian Open title on Saturday and cement her standing as the new queen of the women's game.
Women's champion Serena Williams, bidding for her 22nd Grand Slam title, will have to overcome No 4 seed Agnieszka Radwanska in the first singles semi-final at the Rod Laver Arena.
Stefanos Tsitsipas moved into the Australian Open final on Friday, taking a step towards becoming the first Greek world number on.
German youngster Alexander Zverev pulled off the biggest win of his career on Sunday when he beat world number two Novak Djokovic 6-4, 6-3 to win the Italian Open on Sunday.
That was the lesser of two disappointments for the Belarusian on Thursday, as Azarenka's bid for a third title at Melbourne Park ended with some regret at her missed chances against 22nd seed Rybakina.
Nadal pulled off his greatest escape to deny Daniil Medvedev again, less than three years after leaving the Russian heartbroken in five sets at the 2019 US Open final.
Ash Barty ended Australia's 44-year wait for a home winner at the Australian Open when the world number one staved off a fightback from American Danielle Collins to complete a 6-3, 7-6(2) win on Saturday and pick up her third Grand Slam title.
Novak Djokovic's ability to play his best tennis under pressure can help him win at least five more Grand Slam titles, John McEnroe said after the World No.1 tied Roger Federer and Rafael Nadal's record with his 20th major at Wimbledon on Sunday.
Novak Djokovic advanced to a record-extending 10th Australian Open final with an emphatic win over American Tommy Paul.
Serbia's Novak Djokovic outclasses Russia's Andrey Rublev to set up a meeting with unseeded Tommy Paul in the semi-finals of the Australian Open on Wednesday.
Medvedev will be glad to play the role of dream wrecker once again.
